

New journey starts with today¡¦s research
Merry Christmas and Happy New Year!!!
December 2011
Table of Contents
I. Seasons¡¦ Greetings from President and Board Chair
II. Major Events with ICHTS Participation
III. ICHTS Upcoming Major Events
IV. News on ICHTS-Mainland Collaborative Centers
VII. Message from Editor of Newsletter
Dear Friends and Colleagues of ICHTS Community,
On behalf of the ICHTS and its Board of Directors, we would like to wish everyone a Merry Christmas and a Happy New Year. We sincerely hope that you and your family will have another successful and productive year in 2012!!!
The ICHTS is a unique community where investigators with Chinese heritage in musculoskeletal medicine and science help each other in career development, research advocacy, and promotion of interests of people with Chinese heritage in clinics, research, and industry. The ICHTS has become a mature society in terms of its membership and leadership. Interestingly, this is also reflected by its ¡§teenage¡¨ age of 17. The ICHTS has began to receive recognitions for its unique values in many major professional societies, such as American Society for Bone and Mineral Research, Orthopaedic Research Society, International Bone and Mineral Society, Chinese Medical Association, and Chinese Orthopaedic Associations. For example, both American Society for Bone and Mineral Research and Orthopaedic Research Society have expressed interests in working with ICHTS to outreach to musculoskeletal research communities in China and Asia. Our successful International Conference on Osteoporosis and Bone Research with the Chinese Medical Association, and the International Bone and Mineral Society has been emerged as a major go-to international conference in Asia.
In 2012, we wish to strengthen our community by improving our leadership infrastructure of the Society, enhancing scientific, academic, and translational exchanges within the society and with our partner societies via improved internet portal and infrastructure, promoting career development and involvement of young and woman investigators in the society, developing unique ICHTS Musculoskeletal Summit Workshop, and establishing mutually beneficial and synergistic platforms with our partner societies.
We are looking forward to working for you in 2012.

X. Edward Guo Hong Zhou
President Chair of BOD
1. ICHTS Membership Meetings at ASBMR in San Diego, California
The ASBMR ICHTS Membership Meeting was held between 7:00 pm-9:00pm at Elizabeth Ballroom A, Manchester Grand Hyatt, San Diego, CA, on September 18, 2011 (Sunday). About one hundred (100) ICHTS members and guests attended the meeting. The meeting was commenced with the announcement by the Program Committee Chair, Prof. Xiaodu Wang (UTSA). Then, Dr. Edward X. Guo introduced the keynote speaker, Dr. John P. Bilezikian, Past President of ASBMR and Dorothy L. and Daniel H. Silberberg Professor of Medicine and Pharmacology, Columbia University. Dr. Bilezikian¡¦s presentation was titled ¡§Parathyroid Hormone: how one molecule has defined a career in biomedical research.¡¨ Next, Prof. Lin Qin (HK), the 8th President of ICHTS, delivered his term report as the 8th President of ICHTS. Thereafter, a short inauguration ceremony was given to the 9th ICHTS President, Prof. X. Edward Guo of Columbia University. The Webster Jee Young Investigator Awards was announced by the Award Committee Chair, Prof. X. Wang. Finally, the ICHTS Service Awards and Recognition of Life Time Membership were also announced.

The three winners of 2011 ASBMR Webster Jee Young Investigator Award are: Dr. Kai Li, Medical School of Brown University; Dr. Tian-Fang Li, Center for Musculoskeletal Research, University of Rochester; and Dr. Ge Zhang, Orthopaedics & Traumatology, Chinese University of Hong Kong. The following ICHTS members served on the review panel for the award: Dr. Liangping Xing (URMC), Dr. Wei Yao (UC Davis), Dr. Tingting Tang (SJTU), Dr. Sherry Liu (Columbia), Dr. Gang Li (CUHK), Dr. William Wu (Henry Ford), and Dr. Chao Wang (CUHK). The Award Committee includes Prof. Xiaodu Wang (UTSA), Prof. Di Chen (URMC), Prof. Gang Li (CUHK), Prof. Hong Zhou (US), Prof. Yebin Jiang (UM).

President Ling Qin handed the ¡§Serving People¡¨ Pen to New President Dr. X Edward Guo and Dr. Xiaodu Wang with Web Jee Award Winners
2. 2011 ICHTS Elections
The BOD of ICHTS has adopted leadership restructuring plan and it has been implemented in 2011 election. The significant changes are that President-Elect, President, and Immediate Past President, as well as several key Committee Chairs (Membership, Communication, China Development, and Program Committees) are elected to be automatic members of the BOD. In 2011 election, more than 160 members have voiced their preferences. We are pleased to announce the following results of election
Xu Cao, Johns Hopkins, President-Elect (Chair of Program Committee)
Ling Qin, University of Pennsylvania, Chair of Membership Committee
Tingting Tang, Shanghai Jiaotong University, Chair of China Development Committee
James H-C. Wang, University of Pittsburgh, Chair of Communication Committee

Dr. Yixian Qin with Tinting Tang, Ling Qin (US), Xu Cao, and Ling Qin (Hong Kong) (left to right at ASBMR ICHTS Meeting) and James Wang (right)
2011-2013 Executive Committee
X. Edward Guo, President
Xu Cao, President-Elect (Chair of Program)
Ling, Qin (HK), Immediate Past President
Ling Qin (USA), Chair of Membership
James H-C. Wang, Chair of Communication
Tingting Tang, Chair of China Development
Hong Zhou, Chair of BOD (Ex Officio), Fundraising, and Women
Senior Advisers
Yixian Qin, Last Past President
Gang Li, Chair of Education
David Ke, Past President
Xiaodu Wang, Past Chair of Program
2010-2013 Program Committee
Xu Cao, Chair
Xiaodu Wang
Fanxin Long
Tianfang Li
Meiqing Wang
Qianming Chen
2011-2013 Communication Committee
James H-C. Wang, Chair
Yao-Zhong Liu, Editor of ICHTS E-Update (newsletter)
Xuanliang Neil Dong
Jay Cao
Bin Li
Chi Zhang
Membership Committee
Ling Qin, Chair
Dengshun Miao
Yongjun Liu
Qin Shi
Yingqi Hua
2011-2013 China Development Committee
Tingting Tang, Chair
Cheng-kung Cheng
Deng-shun Miao
Gang Li
Guo-xian Pei
Hui-lin Yang
Jiang Peng
Liao Cui
Ling Qin
Li-yang Dai
Mei-shu Shih
Qing Jiang
Shi-he Li
William W. J. Lu
Yong-jun Wang
2011-2013 Fundraising Committee
Hong Zhou, Chair
Yixian Qin
David Ke
Qian Chen
Ling Qin (Hong Kong)
Linda Ma
Mei Li
2011-2013 Women¡¦s Committee
Hong Zhou, Chair
Ling Qin (US)
Lianping Xing
Xiaoling Zhang
Shuying Yang
Jake Xu
2011-2013 Education Committee
Gang Li, Chair
Zhiyong Zhang
Yunzhi Peter Yang
Chao Wan
Yi-Ping Li
2011-2013 Nomination Committee
Ling Qin (Hong Kong), Chair
X. Edward Guo
Xu Cao
Yixian Qin
Hong Zhou
David Ke
Qian Chen
3. 2011 ICHTS Web Survey
Survey Questions and Results:
1) How do you like the current ICHTS website (http://www.ichts.org)?
28 people (30.8%) responded ¡§Good enough¡¨, 22 people (24.2%) responded ¡§Too simple, not attractive to readers¡¨, 38 people (41.8%) responded ¡§Need more updates¡¨ and 3 people (3.3%) responded ¡§I don¡¦t care¡¨.
2) Would you like a new column ¡§News from members¡¨, where the members can share with other people their important events, such as a new paper, a recent talk, etc.?
62 people (66.7%) responded ¡§Definitely¡¨, 27 people (29%) responded ¡§Possibly¡¨, 2 people (2.2%) responded ¡§Unlikely¡¨ and 2 people (2.2%) responded ¡§No¡¨.
3) Would you like Discussion/Community features so that members can interact online?
40 people (43%) responded ¡§Definitely¡¨, 45 people (48.4%) responded ¡§Possibly¡¨, 5 people (5.4%) responded ¡§Unlikely¡¨ and 3 people (3.2%) responded ¡§No¡¨.
4) Would you like a Job Opportunity section such that members can exchange employment information?
77 people (82.8%) responded ¡§Definitely¡¨, 14 people (15.1%) responded ¡§Possibly¡¨, 1 people (1.1%) responded ¡§Unlikely¡¨ and 1 people (1.1%) responded ¡§No¡¨.
5) Would like an Education section where ICHTS official research and education webinars can be posted online for member only access?
70 people (76.1%) responded ¡§Definitely¡¨, 16 people (17.4%) responded ¡§Possibly¡¨, 5 people (5.4%) responded ¡§Unlikely¡¨ and 1 people (1.1%) responded ¡§No¡¨.
6) How often would you expect the ICHTS website to be updated?
61 people (65.6%) responded ¡§Once a month¡¨, 24 people (25.8%) responded ¡§Once a quarter¡¨, 1 people (1.1%) responded ¡§Once a half year¡¨ and 7 people (7.5%) responded ¡§Other¡¨.
7) What¡¦s the primary ¡§action¡¨ you take when coming to the ICHTS website?
17 people (18.5%) responded ¡§Become a member¡¨, 69 people (75%) responded ¡§Search for information¡¨, 4 people (4.3%) responded ¡§Apply for society award¡¨ and 2 people (2.2%) responded ¡§Other¡¨.
8) Would you like a keyword-based search feature available at the ICHTS website?
53 people (57%) responded ¡§Definitely¡¨, 32 people (34.4%) responded ¡§Possibly¡¨, 5 people (5.4%) responded ¡§Unlikely¡¨ and 3 people (3.2%) responded ¡§No¡¨.
9) Would you like a smart phone friendly feature for the ICHTS website?
23 people (25%) responded ¡§Definitely¡¨, 36 people (39.1%) responded ¡§Possibly¡¨, 25 people (27.2%) responded ¡§Unlikely¡¨ and 8 people (8.7%) responded ¡§No¡¨.
10) Would you like both Chinese and English versions for the ICHTS website?
33 people (35.5%) responded ¡§Definitely¡¨, 42 people (45.2%) responded ¡§Possibly¡¨, 6 people (6.5%) responded ¡§Unlikely¡¨ and 12 people (12.9%) responded ¡§No¡¨.
11) Would you like a site map and a contact page in the ICHTS website?
50 people (55.6%) responded ¡§Definitely¡¨, 36 people (40%) responded ¡§Possibly¡¨, 2 people (2.2%) responded ¡§Unlikely¡¨ and 2 people (2.2%) responded ¡§No¡¨.
12) What¡¦s the platform you use when visiting the ICHTS website?
77 people (82.8%) responded ¡§Windows (2000/XP/Vista/7)¡¨, 15 people (16.1%) responded ¡§Mac OS¡¨, Nobody responded ¡§ Linux¡¨ and nobody responded ¡§Other)
13) What¡¦s the browser you use when coming to the ICHTS website?
42 people (45.2%) responded ¡§Internet Explorer¡¨, 28 people (30.1%) responded ¡§Mozilla Firefox¡¨, 11 people (11.8%) responded ¡§Safari¡¨, 10 people (10.8%) responded ¡§Google Chrome¡¨ and 2 people (2.2%) responded ¡§Other¡¨.
14) What is your suggestion to improve the ICHTS website?
24 people answered the question. Examples:
¡§Provide more information¡¨, ¡§First page attractive. Clearly highlight the folders with pull down list. Graphic and possible animations¡¨, ¡§Professional design¡¨, ¡§ Icon pictures next to the update whenever appropriate¡¨ ¡§ Send e-mail to readers when some new content added to the website.¡¨
More detailed results of the survey are provided in the following link:
http://www.ichts.org/docs/WebDesignSurvey/SurveySummary.html.
4. ICHTS China Development Committee Meeting

On December 3rd, 2011, the China Development Committee held its first Committee meeting at Naton Institute of Medical Technology in Beijing. ICHTS President X. Edward Guo and past Presidents Yi-xian Qin and Di Chen also presented at the meeting. Prof. Ting-ting Tang introduced the composition of China Development Committee. On behalf of ICHTS, X. Edward Guo and Ting-ting Tang issued the appointment letter to each committee member and had their picture taken for memento. Objectives of the committee in 2012 will focus on the arrangement of Web Jee ICHTS Imaging and Histomorphometry Workshop, ICHTS BOD meeting and retreat of ICOBR, Xi¡¦an, 2012. Prof. Guo-xian Pei expressed the confidence of successfully holding the meeting.
1. 2012 ORS-ICHTS Membership Meeting
New in 2012 ORS Membership Meeting: The ORS will video-telecast 2012 ORS-ICHTS Meeting. Webster Jee Young Investigators will be highlighted at the meeting by giving short presentation of their successful stories.
Meeting Description: The International Chinese Hard Tissue Society (ICHTS) will hold 2012 ORS-ICHTS Membership Meeting on February 4th (Saturday), 2012 at Room 2002-04 Moscone West Convention Center, San Francisco, California. This meeting is organized to provide a forum for ICHTS members to exchange information in frontiers of recent musculoskeletal research, to bridge the knowledge gap between the scholars from different research fields, to promote young investigators in the field for successful career developments, and to share the successful experience in career development with senior researchers.
Meeting Schedule:
6:30 PM Registration, sales of ICHTS items, and social exchange provided with food and drink
7:00 PM ORS and China
ORS President, Dr. Brian Johnstone, PhD
7:10 PM ICHTS and China
ICHTS President, Dr. X. Edward Guo, PhD
7:20 PM Keynote Speech
¡§ICHTS and My Career: From Academics to Amgen¡¨
Dr. David Ke, Executive Scientific Director, Amgen. Inc.
7:50 PM Announcement of WJ Young Investigator Awards
Award Committee
7:55 PM Awardees¡¦ Success Story (4 minutes with one slide)
8:15 PM Introduction of New BOD Members
Nomination committee
8:25 PM ICHTS President Closing Remarks
Dr. X. Edward Guo, PhD
8:30 PM Adjourn
Webster Jee Young Investigator Award: To recognize the achievement of young ICHTS members, five (5) Webster Jee Young Investigator Awards will be given at the meeting. The winners will be announced before the membership meeting and they will receive an award certificate and a $300 check at the meeting. All applicants are asked to attend the meeting because the award will be given only to the recipients who attend. Applicants may find details about the 2012 ORS-ICHTS Membership Meeting on the ICHTS website: http//www.ichts.org.
Eligibility for the award: (1) Current ICHTS member; (2) First author of accepted ORS abstracts for 2012 annual meeting; (3) Current graduate and/or medical student; (4) Post-doc or equivalent; (5) Junior faculty and professionals who obtained PhD or MD less than 5 years, and (6) Has not received the award previously.
Winner selection: The accepted ORS abstracts in both blind and un-blind formats should be submitted to both of the following e-mail addresses: ruiyunfeng@126.com and ichts.org@gmail.com no later than January 04, 2012. All submitted abstracts will be peer reviewed in blind by a panel appointed by ICHTS Award Committee. The top scored abstracts will be selected as the winners of Webster Jee Young Investigator Award. As a general rule, no more than one award will be given to the applicants from the same research group.
ICHTS 2012 ORS Webster Jee Award Committee: Prof. Gang Li (Hong Kong, Chair); Prof. Xiaodu Wang (USA); Prof. Cao Xu (USA); and Prof. Tianfang Li (USA)
2. 2012 ICOBR
The third joint CMA-IBMS-ICHTS congress, 2012 ICOBR will be taking place in September 20-23, 2012 in Xi¡¦an, a city records the great changes of the country just like a living history book.

Organized by: Chinese Medical Association (CMA), Chinese Society of Osteoporosis and Bone Mineral Research (CSOBMR), International Bone and Mineral Society (IBMS) and International Chinese Hard Tissue Society (ICHTS).
Organizing Committee Members: Eryuan Liao (co-chair), Yixian Qin (co-chair), Hank Kronenberg (co-chair), Hua Lin, Zhenlin Zhang, Mingquan Li, Xiaodong Guo, Yue Ding, Gang LI, Edward Guo, Xu Cao, Ling Qin, Steve Cummings, Jane Aubin, Robert Nissenson
Scientific Program Committee Members: Ling Xu (co-chair), Hong Zhou (co-chair), Steve Cummings (co-chair), Weibo Xia, Mingcai Qiu, Mei Zhu, Mei Li, , Qian Chen, Ed Guo, Ting Ting Tang, Ling Qin, Hank Kronenberg, Jane Aubin, Robert Nissenson, Ian Reid
Details of 2012 ICOBR will be available soon at homepages: www.csobmr.org.cn/2012, www.ibmsonline.org, or www.ICHTS.org.
3. ICHTS Bone Workshop
The fourth ICHTS Webster Jee Histomorphometry & Imaging Workshop will be held during the September 18 -19, 2012 in Xi¡¦an, China, proceeding the sixth International Conference on Osteoporosis and Bone Research (ICOBR), September 20-23, 2012 in Xi¡¦an¡Athe capital city of Shanxi province of China, which boasts its long history, diverse culture and beautiful scenery, with the famous Silk Road, Terra-cotta Soldiers, Wild Goose Pagoda, Famen Temple, Stele Forest, Huashan mountain, etc.
The Workshop will cover topics on assessment of fracture healing and bone defect repair using histomorphometry and in vivo imaging, and related biomechanics and biomaterials study. SCI paper writing workshop and introduction to leading journals by editors or member of editorial board of leading journals will also be the highlights of the Workshop. We hope to enhance the knowledge of the histomorphometry, in vivo imaging, and biomechanics in the analyses of treatment efficacy of bone diseases and injuries.
Opening of ¡§ICHTS-CUHK Collaborating Center in Chinese University of Hong Kong¡¨
The
1st CUHK International Symposium on Stem Cell Biology and Regenerative Medicine
was successfully held in the Prince of Wales Hospital, The Chinese University
of Hong Kong, Hong Kong on 6 December 2011. Prof. Li Gang, Chair of ICHTS
International Committee was one of the main organizers. There are more than 200
participants attend this symposium including many senior members of ICHTS, such
as Profs. Ed Guo, Ling Qin (HK), Di Chen, Qian Chen, Yi-xian Qin, Tingting
Tang, Yiping Li, Chao Wan, etc, whose presence has made this symposium a truly
international one and an very enjoyable occasion.
At the symposium, the opening ceremony of ICHTS-CUHK-ORT
collaborating Laboratory was lunched with the presence of Prof. Fok, dean of
medical faculty of CUHK; Prof. Ed Guo, the president of ICHTS; Prof. Ling Qin,
the immediate past president of ICHTS; Prof. Gang Li, Chair of Education
Committee, ICHTS, and Prof. KM Chan and Prof. KM Hung, the leaders of CUHK-ORT
department. Prof. Ed Guo, Prof. Ling Qin and Prof. Hung KM have briefly
addressed the audience about the ICHTS and its missions, and the opening
ceremony was followed by intense 1 day symposium on the topics of stem cell
research and regenerative medicine. ICHTS Education committee will plan to
continue to have the similar symposium in 2012 in Hong Kong to provide a
platform for exchange; and welcome ICHTS members to join us in Hong Kong in
2012.

Left: Opening ceremony of ICHTS-CUHK-Collaborating Center at 6 December 2011, in Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong. Right: Prof. Ed Guo addressed the audience about ICHTS.
Total new members in 2011 is 96

Dr. Chi Zhang from University of Texas Southwestern Medical Center
1. have become PLoS ONE Editorial Board member as one of Academic Editors.
2. his paper ¡§Transcriptional Regulation of Vascular Endothelial Growth Factor (VEGF) by Osteoblast-specific Transcription Factor Osterix (Osx) in Osteoblasts¡¨ has been accepted in JBC in Nov, 2011. http://www.ncbi.nlm.nih.gov/pubmed/22110141 The paper provided the first evidence that osteoblast-specific transcription factor Osx controlled VEGF expression, suggesting a potential role of Osx in coordinating osteogenesis and angiogenesis
Dr. Zhifeng Sheng
Recently, Dr sheng et al from china mainland firstly reported that in central south Chinese postmenopausal women, serum sclerostin is lower in women with osteoporosis than without. Serum sclerostin is positively correlated with fat mass and BMD for the whole body, lumbar spine and hip. This paper , entitled¡¥Serum sclerostin level was positively correlated with bone mineral density in central south Chinese postmenopausal women¡¨has been accepted by the IOF Regionals - 2nd IOF Asia-Pacific Osteoporosis and Bone Meeting, and selected as one of the top 8 from a field of over 300 submitted abstracts for the IOF Young Investigator Award.
Dear members and colleagues:
A new email account (ichts.update@gmail.com) has been set up for you to submit or share information in ICHTS E-newsletter. You may send any of the following materials to this email account for distribution:
¢X ICHTS major meetings and events.
¢X Grant awards and/or major publications that are thought to be of high scientific and/or social impact.
¢X Members recognitions.
¢X Job and education opportunities.
¢X Others.
Thanks!
Yao-Zhong Liu, M.D., Ph.D.
Associate Professor
Dept. of Biostatistics and Bioinformatics
Center for Bioinformatics and Genomics
Tulane University School of Public Health and Tropical Medicine
New Orleans, LA